Aripiprazole improves social interaction in Taiwanese children with pervasive developmental disorder.
نویسندگان
چکیده
Aripiprazole, an atypical antipsychotic, is effective in children with psychosis and few adverse effects have been reported. However, little is known about the efficacy and safety of aripiprazole in the treatment of autistic or other pervasive developmental disorders. We report three children with pervasive developmental disorders who were treated with aripiprazole for associated behavioral syndromes. Aripiprazole significantly improved the social interaction of all three children. Furthermore, two patients also showed significant improvement in depression/anxiety syndromes. The outcomes achieved with aripiprazole in these cases suggest that it is a potential therapeutic agent for children with pervasive developmental disorders.
منابع مشابه
Efficacy and Safety of Aripiprazole for Treatment of Irritability in Children with Autistic Disorder: An Open-Label Study
متن کامل
Retrospective Case Series of Aripiprazole Augmentation in Pervasive Developmental Disorders
Due to co-morbidities and treatment resistant nature of pervasive developmental disorder (PDD), diverse combinations of regimens have been tried. This retrospective study aimed to explore adjunctive use of aripiprazole in children with PDD. Changes in illness severity were measured by Clinical Global Impression of Severity (CGI-S) and Clinical Global Impression of Improvement (CGI-I) in 14 arip...
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Autism spectrum disorders (ASD) are neuropsychiatric disorders characterized by impairment in social interactions, in verbal and non-verbal communication, and restricted and stereotyped patterns of interest and behavior within the first 3 years of life. Pharmacologic interventions may be needed for the treatment of temper tantrums, aggression, hyperactivity, and stereotypes in children with ASD...
متن کاملبررسی میزان شیوع انواع اختلالات فراگیر رشد بر حسب جنسیت در نمونه ای از کودکان ایرانی مراجعه کننده به مراکز درمانی و توانبخشی
Introduction & Objective: According to significance of pervasive developmental disorders (PDD) in children and the increasing rate of its prevalence in referred patients to clinic in recent years and due to absence of any report about the rate of PPD in our country, this study was carried out. The aim of this study was to determine the prevalence of PPD in a sample of Iranian children who refer...
متن کاملنیازسنجی حمایت اجتماعی مادران کودکان درخودمانده
Autism is a pervasive developmental disorder which has pervasive effects on a wide range of child developmental categories and in addition to the individual, the family heavily involved in numerous behavioral problems and are grueling their rehabilitation. Hence, providing support programs can reduce this heavy burden on the parents and it is somewhat effective. The study examined the social su...
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عنوان ژورنال:
- Chang Gung medical journal
دوره 33 2 شماره
صفحات -
تاریخ انتشار 2010